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Pharmacology and pharmacokinetics
Sep 20, 2017

The chemical structure of lenalidomide is similar to thalidomide. Although  the exact mechanism of action of lenalidomide is not yet clear, it has  been known that lenalidomide has immunoregulatory and anti-angiogenic  effects. After oral administration, lenalidomide is rapidly absorbed into the body. In vitro experiments showed that lenalidomide plasma protein binding rate of about 30%. Approximately 2/3 of lenalidomide is excreted in the form of urine, with a half elimination of about 3 hours.

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